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单玉萍  讲师


2013.08--  现在:博士后访问学者  美国南卡大学化学与生物化学系(Qian Wang教授课题组)

2012.02--2013.07:博士后访问学者  美国佛罗里达国际大学物理系(Jin He课题组)

2008.09--2011.11:理学博士  中国科学院长春应用化学研究所电分析化学国家重点实验室

2010.12--2011.02:学术交流访问  奥地利开普勒林茨大学生物物理研究所(Peter Hinterdorfer教授课题组)

2005.09--2008.07:理学硕士  东北师范大学多酸化学教育部重点实验室

2001.09--2005.07:理学学士  哈尔滨师范大学化学系


联系方式:Email: xiaoshan9999@hotmail.com


研究方向及兴趣

  1. 通过原子力显微镜单分子力谱技术研究点击化学的动力学性质、作用过程及其点击化学在活体细胞表面的应用

  2. 基于原子力显微镜力示踪技术研究单个流感病毒及单个纳米粒子入侵宿主细胞膜的动态过程 


主持和参与科研项目

  1. 国家自然科学青年基金:力示踪方法研究单个流感病毒入侵宿主细胞膜的动态过程,(21303181),项目起止时间:2014.01-2016.12,本人为项目负责人(25万)

  2. 国家自然科学重点基金:在单病毒粒子水平研究石斑鱼虹彩病毒SGIV侵染宿主细胞的机制(31330082),项目起止时间:2014.01-2018.12,本人为主要参加人,负责本项目的单分子力谱研究部分



发表及待发表论文

  1. Yuping Shan and Hongda wang,“The structure and function of cell membranes examined with atomic force microscopy and single-molecule force spectroscopy”, Chemical society Reviews, 邀请综述修改中,影响因子:30.425,化学综合1区杂志  

  2. Yangang Pan#, Shaowen Wang#, Yuping Shan#, Dinglin Zhang, Jing Gao, Min Zhang, Shuheng Liu, Mingjun Cai, Haijiao Xu, Guohui Li, Qiwei Qin and Hongda Wang, “Ultrafast tracking of a single live virion during the invagination of a cell membrane”, Small, Accept, # 共同第一作者, 影响因子:7.514, VIP文章,化学综合1区杂志 

  3. Yangang Pan*, Fuxian Zhang*, Yuping Shan*, Shuheng Liu, Mingjun Cai, Hanzhong Wang and Hongda Wang, “The membrane invagination and force of viral endocytosis measured by a force tracing technique” Scientific Reports, Accept,*共同第一作者,影响因子:5.078,Nature group杂志,综合性期刊2区杂志  

  4. Yuping Shan, Jinfeng Huang, Juanjuan Tan, Gui Gao, Hongda Wang, Yuxin Chen, “The study of single anticancer peptides interacting with HeLa cell membranes by single molecule force spectroscopy”, Nanoscale, 2012, 4, 1283–1286. 影响因子:6.739,杂志内封面,化学综合1区杂志  

  5. Yuping Shan, Suyong Ma, Liya Nie, Xin Shang, Xian Hao, Zhiyong Tang, Hongda Wang, “Size-dependent endocytosis of single gold nanoparticle”, Chem Commun, 2011, 47(28), 8091–8093. 影响因子:6.718,化学综合2区杂志  

  6. Yuping Shan, Xian Hao, Xin Shang, Mingjun Cai, Junguang Jiang, Zhiyong Tang, and Hongda Wang, “Recording force events of single quantum-dot endocytosis”, Chem Commun, 2011, 47(12), 3377–3379. 影响因子:6.718,Nature Asia materials亮点报道,化学综合2区杂志  

  7. Xin Shang, Yuping Shan, Yangnag Pan#, Mingjun Cai, Junguang Jiang, Hongda Wang, “The force of transporting a single amino acid into the living cell measured by atomic force microscopy”, Chem Commun. 2013, 49, 8163-8165 #共同第一作者,影响因子:6.718,化学综合2区杂志  

  8. Yuping Shan, P B Tiwari, P Krishnakumar, I Vlassiouk, Wenzhi Li, Xuewen Wang, Y Darici, S M Lindsay, Hongda Wang, S Smirnov, Jin He, “Surface modification of graphene nanopores for protein translocation”, Nanotechnology, 2013, 24 495102. doi:10.1088/0957-4484/24/49/495102. 影响因子:3.672,纳米科技2区杂志  

  9. Yuping Shan, Guocheng Yang, Jian Gong, Xiaoli Zhang, Liande Zhu, Lunyu Qu, “Prussian blue nanoparticles potentiostatically electrodeposited on ITO/chitosan nanofibers electrode and their electrocatalysis towards hydrogen peroxide”, Electrochim Acta, 2008, 53(26), 7751–7755. 影响因子:4.287,电化学2区杂志  

  10. Yuping Shan, Guocheng Yang, Yongtang Jia, Jian Gong, Zhongmin Su, Lunyu Qu, “ITO electrode modified with chitosan nanofibers loading polyoxometalate by one step self-assembly method and its electrocatalysis”, Electrochem Commun, 2007, 9, 2224–2228. 影响因子:4.425  电化学1区杂志  

  11. Yuping Shan, Guocheng Yang, Yongling Sun, Shujie Pang, Jian Gong, Zhongmin Su, Lunyu Qu, “ITO electrode modified by self-assembling multilayer film of polyoxometallate on poly (vinyl alcohol) nanofibers and its electrocatalytic behavior”, Electrochim Acta, 2007, 53, 569–574. 影响因子:4.287,电化学2区杂志  

  12. Yuping Shan, Zhiyong Wang, Xian Hao, Xin Shang, Mingjun Cai, Junguang Jiang, Xuexun Fang, Hongda Wang and Zhiyong Tang. “Locating the BandIII protein in quasi-native cell membranes”, Anal Methods, 2010, 2(7), 805–808. 影响因子:1.855 杂志封面,分析化学3区杂志   

  13. Junguang Jiang, Xian Hao, Mingjun Cai, Yuping Shan, Xin Shang, Zhiyong Tang, and Hongda Wang.  “Localization of Na+-K+ ATPases in quasi-native cell membranes”, Nano Letters, 2009, 9(12), 4489–4493. 影响因子:12.94,化学综合1区杂志  

  14. Xian Hao, Xin Shang, Mingjun Cai, Yuping Shan, Jiazhen Wu, Junguang Jiang, Hongda Wang. “Single-particle tracking of hepatitis B virus-like vesicle entry into cells”, Small, 2011, 7(9), 1212–1218. 影响因子:7.514,杂志封面,化学综合1区杂志 

  15. Bohua Ding , Yongmei Tian, Yangang Pan, Yuping Shan, Mingjun Cai, Haijiao Xu, Yingchun Sun and Hongda Wang. “Recording the dynamic endocytosis of single gold nanoparticles by  AFM-based Force Tracing”,  Nanoscale, in revision, 影响因子:6.739,化学综合1区杂志   

  16. Xian Hao, Jiazhen Wu, Yuping Shan, Mingjun Cai, Xin Shang, Junguang Jiang and Hongda Wang, “Caveolae-mediated endocytosis of biocompatible gold nanoparticles in living Helacells”, 2012, 24, J. Phys.: Condens. Matter, doi:10.1088/0953-8984/24/16/164207. 影响因子:2.223,凝聚态物理3区杂志  

  17. Hongda Wang, Xian Hao, Yuping Shan, Junguang Jiang, MingjunCai, Xin Shang. “Preparation of cell membranes for high resolution imaging by AFM”, Ultramicroscopy, 2010, 110(4), 305–312. 影响因子:2.745,显微镜技术2区杂志  

  18. Yongling Sun, Yuping Shan, Xiujun Cui, Bin Li, Jian Gong, Zhongmin Su, Lunyu Qu,“Investigation on fluorescence properties of ultra-fine PVA fiber mats containedpolyoxometalate with different molecular structure”, J Appl Polym Sci, 2009, 113(3), 1369–1374. 影响因子:1.64,高分子科学4区杂志


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